Xiangrui Li Selected Research

DNA Vaccines

12/2021	Eimeria maxima Rhomboid-like Protein 5 Provided Partial Protection against Homologous Challenge in Forms of Recombinant Protein and DNA Plasmid in Chickens.
11/2018	Protective immunity induced by Eimeria common antigen 14-3-3 against Eimeria tenella, Eimeria acervulina and Eimeria maxima.
4/2017	Immune protection duration and efficacy stability of DNA vaccine encoding Eimeria tenella TA4 and chicken IL-2 against coccidiosis.
10/2016	Evaluation of the persistence, integration, histopathology and environmental release of DNA vaccine encoding Eimeria tenella TA4 and chicken IL-2.
11/2015	Protective immunity against acute toxoplasmosis in BALB/c mice induced by a DNA vaccine encoding Toxoplasma gondii 10 kDa excretory-secretory antigen (TgESA10).
10/2015	Immune protection of microneme 7 (EmMIC7) against Eimeria maxima challenge in chickens.
10/2015	Eimeria maxima microneme protein 2 delivered as DNA vaccine and recombinant protein induces immunity against experimental homogenous challenge.
9/2015	Chimeric DNA vaccines encoding Eimeria acervulina macrophage migration inhibitory factor (E.MIF) induce partial protection against experimental Eimeria infection.
9/2015	Efficacy of chimeric DNA vaccines encoding Eimeria tenella 5401 and chicken IFN-γ or IL-2 against coccidiosis in chickens.
8/2015	Construction of Eimeria tenella multi-epitope DNA vaccines and their protective efficacies against experimental infection.

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Xiangrui Li Research Topics

Disease

34	Infections 06/2022 - 10/2010
17	Body Weight (Weight, Body) 01/2020 - 10/2008
15	Coccidiosis 01/2022 - 10/2008
8	Neoplasms (Cancer) 01/2022 - 01/2015
7	Toxoplasmosis 05/2021 - 11/2015
4	Inflammation (Inflammations) 10/2022 - 10/2016
3	Lung Neoplasms (Lung Cancer) 10/2022 - 02/2018
3	Schistosomiasis (Bilharziasis) 12/2015 - 12/2010
2	Persistent Infection 08/2022 - 08/2020
2	Starvation 01/2021 - 12/2020
2	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 08/2019
2	Coinfection 11/2018 - 06/2015
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2022
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 10/2022
1	Malnutrition (Nutritional Deficiencies) 10/2022
1	Cysts 08/2022
1	Weight Loss (Weight Reduction) 01/2022
1	Squamous Cell Carcinoma of Head and Neck 01/2022
1	Trichinellosis 01/2022
1	Cachexia 12/2021
1	Hypersensitivity (Allergy) 11/2020
1	Nematode Infections 10/2020
1	Pathologic Processes 03/2020
1	Parasitic Diseases (Parasitic Disease) 01/2020
1	Autoimmune Diseases (Autoimmune Disease) 11/2019
1	Disease Progression 12/2018
1	Weight Gain 11/2018
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2018
1	Schizophrenia (Dementia Praecox) 01/2018
1	Trichomonas Infections 01/2018
1	Lung Diseases (Lung Disease) 01/2018
1	Liver Diseases (Liver Disease) 01/2018
1	Hallucinations (Hallucination) 01/2018
1	Heart Diseases (Heart Disease) 01/2017
1	Hypertension (High Blood Pressure) 01/2017

Drug/Important Bio-Agent (IBA)

20	AntigensIBA 08/2022 - 10/2010
19	VaccinesIBA 08/2022 - 11/2006
19	Proteins (Proteins, Gene)FDA Link 08/2022 - 02/2011
19	DNA VaccinesIBA 12/2021 - 10/2008
6	CytokinesIBA 06/2022 - 02/2011
6	Interleukin-2 (IL2)IBA 04/2017 - 11/2006
5	Recombinant ProteinsIBA 08/2022 - 11/2012
4	Subunit VaccinesIBA 12/2021 - 09/2015
4	Biological ProductsIBA 12/2018 - 01/2015
4	Combined VaccinesIBA 11/2018 - 06/2015
3	Indicators and Reagents (Reagents)IBA 10/2022 - 01/2022
3	Interleukin-9 (Interleukin 9)IBA 05/2022 - 01/2020
3	DNA (Deoxyribonucleic Acid)IBA 02/2021 - 04/2010
3	AntibodiesIBA 02/2020 - 12/2012
2	Biomarkers (Surrogate Marker)IBA 10/2022 - 01/2022
2	AlbuminsIBA 01/2022 - 12/2021
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 12/2020
2	Tyrosine (L-Tyrosine)FDA Link 01/2021 - 01/2021
2	Immunoglobulins (Immunoglobulin)IBA 01/2021 - 01/2021
2	InsecticidesIBA 01/2021 - 12/2020
2	Interleukin-4 (Interleukin 4)IBA 04/2020 - 03/2020
2	EnzymesIBA 08/2019 - 02/2013
2	Pharmaceutical PreparationsIBA 01/2018 - 02/2013
2	EpitopesIBA 08/2015 - 06/2015
1	Glucose (Dextrose)FDA LinkGeneric 10/2022
1	ChemokinesIBA 06/2022
1	Carrier Proteins (Binding Protein)IBA 05/2022
1	GlobulinsIBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	C-Reactive ProteinIBA 01/2022
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2022
1	Polylactic Acid-Polyglycolic Acid CopolymerIBA 05/2021
1	ribosomal phosphoprotein P2IBA 04/2021
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2021
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2021
1	ChitosanIBA 01/2021
1	PerforinIBA 01/2021
1	Phosphates (Orthophosphate)IBA 01/2021
1	NAD (NADH)IBA 12/2020
1	Transforming Growth Factors (Transforming Growth Factor)IBA 10/2020
1	Immunologic Factors (Immunomodulators)IBA 08/2020
1	Neurotransmitter Agents (Neurotransmitter)IBA 04/2020
1	Immunoglobulin G (IgG)IBA 04/2020
1	Dopamine (Intropin)FDA LinkGeneric 04/2020
1	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 04/2020
1	Metalloproteases (Metalloproteinases)IBA 03/2020
1	Prealbumin (Transthyretin)IBA 03/2020
1	TropomyosinIBA 02/2020
1	Immune Sera (Antisera)IBA 01/2020
1	Interleukin-17 (Interleukin 17)IBA 11/2019
1	ImmunosorbentsIBA 08/2019
1	Hormones (Hormone)IBA 04/2019
1	Cathepsin BIBA 01/2019
1	Cysteine Proteases (Cysteine Protease)IBA 01/2019
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2018
1	Lactic Acid (Lactate)FDA LinkGeneric 02/2018
1	Genetic Markers (Genetic Marker)IBA 01/2018
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2018
1	Peptide Elongation Factors (Elongation Factor)IBA 01/2017
1	Vitamin D FDA LinkGeneric 01/2017
1	Hematoxylin (Haematoxylon)IBA 10/2016

Therapy/Procedure

2	Nanospheres 05/2021 - 01/2021
2	Therapeutics 02/2018 - 01/2018
1	Immunotherapy 01/2022
1	Immunomodulation 05/2021